Method for treating cancer using oral arsenic trioxide
The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering effective amount of arsenic trioxide to an affected patient.
Patent Number: US20080089949A1
Application Number: US2006549347A
Inventor: Kwong, Yok-Lam
Priority Date: 13 Oct 2006
Priority Number: US20080089949A1
Application Date: 13 Oct 2006
Publication Date: 17 Apr 2008
IPC Current: A61K003336
US Class: 424623
Title: Method for treating cancer using oral arsenic trioxide
Usefulness: Method for treating cancer using oral arsenic trioxide
Summary: Composition (A) is useful for the treatment of hematological malignancies (preferably acute myeloid leukemia (preferred), acute nonlymphocytic leukemia, myeloblastic leukemia, promyelocytic leukemia, myelomonocytic leukemia, monocytic leukemia, erythroleukemia, myelodysplastic syndrome, acute promyelocytic leukemia (preferred), chronic lymphocytic leukemia, chronic myeloid leukemia, hairy cell leukemia, polycythemia vera, Hodgkin's lymphoma, non-Hodgkin's lymphomas, myeloma, giant cell myeloma, indolent myeloma, localized myeloma, multiple myeloma, plasma cell myeloma, sclerosing myeloma, solitary myeloma, smoldering multiple myeloma, nonsecretary myeloma, osteosclerotic myeloma, plasma cell leukemia, solitary plasmacytoma, and extramedullary plasmacytoma). (all claimed)
Novelty: Preparation of oral composition, useful to treat hematological malignancies, comprises addition of sterile water to arsenic trioxide, followed by subsequent addition of sodium hydroxide and hydrochloric acid to form a solution
诊断/治疗
癌症/肿瘤
香港
